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PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer
Helicobacter pylori (H. pylori) infection is the main risk factor for gastric cancer. The role of antioxidant enzyme peroxiredoxin 2 (PRDX2) in gastric tumorigenesis remains unknown. In vitro (AGS and SNU-1 cell lines) and in vivo mouse models were utilized to investigate the role of PRDX2 in respon...
Autores principales: | Wang, Sen, Chen, Zheng, Zhu, Shoumin, Lu, Heng, Peng, Dunfa, Soutto, Mohammed, Naz, Huma, Peek, Richard, Xu, Hao, Zaika, Alexander, Xu, Zekuan, El-Rifai, Wael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811995/ https://www.ncbi.nlm.nih.gov/pubmed/31536951 http://dx.doi.org/10.1016/j.redox.2019.101319 |
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