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Covalent Aurora A regulation by the metabolic integrator coenzyme A

Aurora A kinase is a master mitotic regulator whose functions are controlled by several regulatory interactions and post-translational modifications. It is frequently dysregulated in cancer, making Aurora A inhibition a very attractive antitumor target. However, recently uncovered links between Auro...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yugo, Byrne, Dominic P., Burgess, Selena G., Bormann, Jenny, Baković, Jovana, Huang, Yueyang, Zhyvoloup, Alexander, Yu, Bess Yi Kun, Peak-Chew, Sew, Tran, Trang, Bellany, Fiona, Tabor, Alethea B., Chan, AW Edith, Guruprasad, Lalitha, Garifulin, Oleg, Filonenko, Valeriy, Vonderach, Matthias, Ferries, Samantha, Eyers, Claire E., Carroll, John, Skehel, Mark, Bayliss, Richard, Eyers, Patrick A., Gout, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812009/
https://www.ncbi.nlm.nih.gov/pubmed/31546169
http://dx.doi.org/10.1016/j.redox.2019.101318