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Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression

Interleukin (IL)-1β and tumor necrosis factor (TNF)-α, in particular, control the degeneration of articular cartilage, making them prime targets for osteoarthritis (OA) therapeutic strategies. Advanced oxidation protein products (AOPPs) are prevalent in numerous diseases. Our previous work demonstra...

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Detalles Bibliográficos
Autores principales: Liao, Cong-Rui, Wang, Sheng-Nan, Zhu, Si-Yuan, Wang, Yi-Qing, Li, Zong-Ze, Liu, Zhong-Yuan, Jiang, Wang-Sheng, Chen, Jian-Ting, Wu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812020/
https://www.ncbi.nlm.nih.gov/pubmed/31539804
http://dx.doi.org/10.1016/j.redox.2019.101306