Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

Ferroptosis is a form of cell death primed by iron and lipid hydroperoxides and prevented by GPx4. Ferrostatin-1 (fer-1) inhibits ferroptosis much more efficiently than phenolic antioxidants. Previous studies on the antioxidant efficiency of fer-1 adopted kinetic tests where a diazo compound generat...

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Detalles Bibliográficos
Autores principales: Miotto, Giovanni, Rossetto, Monica, Di Paolo, Maria Luisa, Orian, Laura, Venerando, Rina, Roveri, Antonella, Vučković, Ana-Marija, Bosello Travain, Valentina, Zaccarin, Mattia, Zennaro, Lucio, Maiorino, Matilde, Toppo, Stefano, Ursini, Fulvio, Cozza, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812032/
https://www.ncbi.nlm.nih.gov/pubmed/31574461
http://dx.doi.org/10.1016/j.redox.2019.101328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812032/
https://www.ncbi.nlm.nih.gov/pubmed/31574461
http://dx.doi.org/10.1016/j.redox.2019.101328

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