Structure-based tailoring of the first coumarins-specific bergaptol O-methyltransferase to synthesize bergapten for depigmentation disorder treatment

Bergapten has long been used in combination with ultraviolet A irradiation to treat depigmentation disorder. However, extremely low bergapten contents in plants and difficulties in synthesizing bergapten have limited its application. Here, we developed an alternative bergapten-production method. We...

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Detalles Bibliográficos
Autores principales: Zhao, Yucheng, Wang, Nana, Wu, Huali, Zhou, Yuanze, Huang, Chuanlong, Luo, Jun, Zeng, Zhixiong, Kong, Lingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812039/
https://www.ncbi.nlm.nih.gov/pubmed/31666994
http://dx.doi.org/10.1016/j.jare.2019.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812039/
https://www.ncbi.nlm.nih.gov/pubmed/31666994
http://dx.doi.org/10.1016/j.jare.2019.10.003

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