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Revealing the Membrane-Bound Catalytic Oxidation of NADH by the Drug Target Type-II NADH Dehydrogenase

[Image: see text] Type-II NADH:quinone oxidoreductases (NDH-2s) are an important element of microbial pathogen electron transport chains and an attractive drug target. Despite being widely studied, its mechanism and catalysis are still poorly understood in a hydrophobic membrane environment. A recen...

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Detalles Bibliográficos
Autores principales: Godoy-Hernandez, Albert, Tate, Daniel J., McMillan, Duncan G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812066/
https://www.ncbi.nlm.nih.gov/pubmed/31592658
http://dx.doi.org/10.1021/acs.biochem.9b00752