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Investigating Phosphorylation-Induced Conformational Changes in WNK1 Kinase by Molecular Dynamics Simulations

[Image: see text] The With-No-Lysine (WNK) kinase is considered to be a master regulator for various cation-chloride cotransporters involved in maintaining cell-volume and ion homeostasis. Here, we have investigated the phosphorylation-induced structural dynamics of the WNK1 kinase bound to an inhib...

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Detalles Bibliográficos
Autores principales: Jonniya, Nisha Amarnath, Sk, Md Fulbabu, Kar, Parimal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812135/
https://www.ncbi.nlm.nih.gov/pubmed/31656913
http://dx.doi.org/10.1021/acsomega.9b02187