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Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

Rett syndrome (RTT) is a progressive neurodevelopmental disorder mainly caused by mutations in the X-linked MECP2 gene. RTT patients show multisystem disturbances associated with an oxinflammatory status. Inflammasomes are multi-protein complexes, responsible for host immune responses against pathog...

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Detalles Bibliográficos
Autores principales: Pecorelli, Alessandra, Cordone, Valeria, Messano, Nicolò, Zhang, Changqing, Falone, Stefano, Amicarelli, Fernanda, Hayek, Joussef, Valacchi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812177/
https://www.ncbi.nlm.nih.gov/pubmed/31606551
http://dx.doi.org/10.1016/j.redox.2019.101334