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Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation
Rett syndrome (RTT) is a progressive neurodevelopmental disorder mainly caused by mutations in the X-linked MECP2 gene. RTT patients show multisystem disturbances associated with an oxinflammatory status. Inflammasomes are multi-protein complexes, responsible for host immune responses against pathog...
Autores principales: | Pecorelli, Alessandra, Cordone, Valeria, Messano, Nicolò, Zhang, Changqing, Falone, Stefano, Amicarelli, Fernanda, Hayek, Joussef, Valacchi, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812177/ https://www.ncbi.nlm.nih.gov/pubmed/31606551 http://dx.doi.org/10.1016/j.redox.2019.101334 |
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