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A real-time ex vivo model (eIBUB) for optimizing intraperitoneal drug delivery as an alternative to living animal models

BACKGROUND: Optimization of intraperitoneal drug delivery systems requires functional models. We proposed the Inverted Bovine Urinary Bladder Model (IBUB), but IBUB does not allow repeated measurements over time and there is a significant biological variability between organs. METHODS: A further dev...

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Detalles Bibliográficos
Autores principales: Sautkin, Iaroslav, Solass, Wiebke, Weinreich, Frank-Jürgen, Königsrainer, Alfred, Schenk, Martin, Thiel, Karolin, Reymond, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812219/
https://www.ncbi.nlm.nih.gov/pubmed/31667331
http://dx.doi.org/10.1515/pp-2019-0017