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A real-time ex vivo model (eIBUB) for optimizing intraperitoneal drug delivery as an alternative to living animal models
BACKGROUND: Optimization of intraperitoneal drug delivery systems requires functional models. We proposed the Inverted Bovine Urinary Bladder Model (IBUB), but IBUB does not allow repeated measurements over time and there is a significant biological variability between organs. METHODS: A further dev...
Autores principales: | Sautkin, Iaroslav, Solass, Wiebke, Weinreich, Frank-Jürgen, Königsrainer, Alfred, Schenk, Martin, Thiel, Karolin, Reymond, Marc A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812219/ https://www.ncbi.nlm.nih.gov/pubmed/31667331 http://dx.doi.org/10.1515/pp-2019-0017 |
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