The nitroxide 4-methoxy-tempo inhibits the pathogenesis of dextran sodium sulfate-stimulated experimental colitis

Inflammatory bowel disease (IBD) is a chronic condition characterised by leukocyte recruitment to the gut mucosa. Leukocyte myeloperoxidase (MPO) produces the two-electron oxidant hypochlorous acid (HOCl), damaging tissue and playing a role in cellular recruitment, thereby exacerbating gut injury. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Chami, Belal, San Gabriel, Patrick T., Kum-Jew, Stephen, Wang, XiaoSuo, Dickerhof, Nina, Dennis, Joanne M., Witting, Paul K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812268/
https://www.ncbi.nlm.nih.gov/pubmed/31593888
http://dx.doi.org/10.1016/j.redox.2019.101333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812268/
https://www.ncbi.nlm.nih.gov/pubmed/31593888
http://dx.doi.org/10.1016/j.redox.2019.101333

Ejemplares similares