Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

Quinones are common in nature, and often cytotoxic. Their proposed toxicity mechanisms involve redox cycling with radical generation, and/or reactions with nucleophiles, such as protein cysteine (Cys) residues, forming adducts via Michael addition reactions. The selenenyl anion of selenocysteine (Se...

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Detalles Bibliográficos
Autores principales: Shu, Nan, Cheng, Qing, Arnér, Elias S.J., Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812298/
https://www.ncbi.nlm.nih.gov/pubmed/31590044
http://dx.doi.org/10.1016/j.redox.2019.101335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812298/
https://www.ncbi.nlm.nih.gov/pubmed/31590044
http://dx.doi.org/10.1016/j.redox.2019.101335

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