Immunogenicity, Lot Consistency, and Extended Safety of rVSVΔG-ZEBOV-GP Vaccine: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults

BACKGROUND: This double-blind study assessed immunogenicity, lot consistency, and safety of recombinant vesicular stomatitis virus-Zaire Ebola virus envelope glycoprotein vaccine (rVSVΔG-ZEBOV-GP). METHODS: Healthy adults (N = 1197) were randomized 2:2:2:2:1 to receive 1 of 3 consistency lots of rVS...

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Detalles Bibliográficos
Autores principales: Halperin, Scott A, Das, Rituparna, Onorato, Matthew T, Liu, Kenneth, Martin, Jason, Grant-Klein, Rebecca J, Nichols, Rick, Coller, Beth-Ann, Helmond, Frans A, Simon, Jakub K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812306/
https://www.ncbi.nlm.nih.gov/pubmed/31505665
http://dx.doi.org/10.1093/infdis/jiz241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812306/
https://www.ncbi.nlm.nih.gov/pubmed/31505665
http://dx.doi.org/10.1093/infdis/jiz241

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