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Immunogenicity, Lot Consistency, and Extended Safety of rVSVΔG-ZEBOV-GP Vaccine: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults

BACKGROUND: This double-blind study assessed immunogenicity, lot consistency, and safety of recombinant vesicular stomatitis virus-Zaire Ebola virus envelope glycoprotein vaccine (rVSVΔG-ZEBOV-GP). METHODS: Healthy adults (N = 1197) were randomized 2:2:2:2:1 to receive 1 of 3 consistency lots of rVS...

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Detalles Bibliográficos
Autores principales:	Halperin, Scott A, Das, Rituparna, Onorato, Matthew T, Liu, Kenneth, Martin, Jason, Grant-Klein, Rebecca J, Nichols, Rick, Coller, Beth-Ann, Helmond, Frans A, Simon, Jakub K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812306/ https://www.ncbi.nlm.nih.gov/pubmed/31505665 http://dx.doi.org/10.1093/infdis/jiz241

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