Two CRISPR/Cas9-mediated methods for targeting complex insertions, deletions, or replacements in mouse

Genetically modified model organisms are valuable tools for probing gene function, dissecting complex signaling networks, studying human disease, and more. CRISPR/Cas9 technology has significantly democratized and reduced the time and cost of generating genetically modified models to the point that...

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Detalles Bibliográficos
Autores principales: Pineault, Kyriel M., Novoa, Ana, Lozovska, Anastasiia, Wellik, Deneen M., Mallo, Moises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812322/
https://www.ncbi.nlm.nih.gov/pubmed/31667107
http://dx.doi.org/10.1016/j.mex.2019.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812322/
https://www.ncbi.nlm.nih.gov/pubmed/31667107
http://dx.doi.org/10.1016/j.mex.2019.09.003

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