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Broadening and Enhancing Functions of Antibodies by Self-Assembling Multimerization at Cell Surface

[Image: see text] Monoclonal antibody therapy has offered treatment benefits. Nonetheless, a lack of efficacy still exists, partially because monovalent binding of antibodies to specific receptors fails to translate into an active response. Here, we report a pretargeting–postassembly approach that e...

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Detalles Bibliográficos
Autores principales: Li, Lian, Wang, Jiawei, Li, Yachao, Radford, D. Christopher, Yang, Jiyuan, Kopeček, Jindřich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812323/
https://www.ncbi.nlm.nih.gov/pubmed/31553883
http://dx.doi.org/10.1021/acsnano.9b04868