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Decapping Scavenger Enzyme Activity toward N2-Substituted 5′ End mRNA Cap Analogues

[Image: see text] mRNA degradation is a key mechanism of gene expression regulation. In the 3′ → 5′ decay pathway, mRNA is degraded by the exosome complex and the resulting cap dinucleotide or short-capped oligonucleotide is hydrolyzed mainly by a decapping scavenger enzyme (DcpS)—a member of the hi...

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Detalles Bibliográficos
Autores principales: Pietrow, Paulina, Ferenc-Mrozek, Aleksandra, Piecyk, Karolina, Bojarska, Elzbieta, Darzynkiewicz, Edward, Jankowska-Anyszka, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812366/
https://www.ncbi.nlm.nih.gov/pubmed/31656932
http://dx.doi.org/10.1021/acsomega.9b02715