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Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism

OBJECTIVE: The dynamic regulation of metabolic pathways can be monitored by stable isotope tracing. Yet, many metabolites are part of distinct processes within different subcellular compartments. Standard isotope tracing experiments relying on analyses in whole cells may not accurately reflect compa...

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Detalles Bibliográficos
Autores principales: Trefely, Sophie, Liu, Joyce, Huber, Katharina, Doan, Mary T., Jiang, Helen, Singh, Jay, von Krusenstiern, Eliana, Bostwick, Anna, Xu, Peining, Bogner-Strauss, Juliane G., Wellen, Kathryn E., Snyder, Nathaniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812369/
https://www.ncbi.nlm.nih.gov/pubmed/31767181
http://dx.doi.org/10.1016/j.molmet.2019.09.004