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Classification of RNA backbone conformations into rotamers using (13)C′ chemical shifts: exploring how far we can go

The conformational space of the ribose-phosphate backbone is very complex as it is defined in terms of six torsional angles. To help delimit the RNA backbone conformational preferences, 46 rotamers have been defined in terms of these torsional angles. In the present work, we use the ribose experimen...

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Detalles Bibliográficos
Autores principales: Icazatti, Alejandro A., Loyola, Juan M., Szleifer, Igal, Vila, Jorge A., Martin, Osvaldo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812668/
https://www.ncbi.nlm.nih.gov/pubmed/31656702
http://dx.doi.org/10.7717/peerj.7904