Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model

Purinergic receptors, especially P2RX, are associated to the severity of symptoms in patients suffering from depressive and bipolar disorders, and genetic deletion or pharmacological blockade of P2RX7 induces antidepressant-like effect in preclinical models. However, there is scarce evidence about t...

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Detalles Bibliográficos
Autores principales: Ribeiro, Deidiane Elisa, Casarotto, Plinio C., Staquini, Laura, Pinto e Silva, Maria Augusta, Biojone, Caroline, Wegener, Gregers, Joca, Samia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Animal Behavior
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812674/
https://www.ncbi.nlm.nih.gov/pubmed/31656696
http://dx.doi.org/10.7717/peerj.7834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812674/
https://www.ncbi.nlm.nih.gov/pubmed/31656696
http://dx.doi.org/10.7717/peerj.7834

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