Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model

Chronic antibody mediated rejection (cAMR) remains a significant barrier to achieving long-term graft survival in kidney transplantation, which results from alloantibody production from B lymphocytes and plasma cells. APRIL (A proliferation-inducing ligand) and BLyS (B lymphocyte stimulator) are cri...

Descripción completa

Detalles Bibliográficos
Autores principales: Bath, Natalie M., Ding, Xiang, Verhoven, Bret M., Wilson, Nancy A., Coons, Lauren, Sukhwal, Adarsh, Zhong, Weixiong, Redfield III, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812745/
https://www.ncbi.nlm.nih.gov/pubmed/31647850
http://dx.doi.org/10.1371/journal.pone.0223889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812745/
https://www.ncbi.nlm.nih.gov/pubmed/31647850
http://dx.doi.org/10.1371/journal.pone.0223889

Ejemplares similares