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Autoantibody production significantly decreased with APRIL/BLyS blockade in murine chronic rejection kidney transplant model

Chronic antibody mediated rejection (cAMR) remains a significant barrier to achieving long-term graft survival in kidney transplantation, which results from alloantibody production from B lymphocytes and plasma cells. APRIL (A proliferation-inducing ligand) and BLyS (B lymphocyte stimulator) are cri...

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Detalles Bibliográficos
Autores principales:	Bath, Natalie M., Ding, Xiang, Verhoven, Bret M., Wilson, Nancy A., Coons, Lauren, Sukhwal, Adarsh, Zhong, Weixiong, Redfield III, Robert R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812745/ https://www.ncbi.nlm.nih.gov/pubmed/31647850 http://dx.doi.org/10.1371/journal.pone.0223889

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