The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population

BACKGROUND: Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role. Cathepsin G (CTSG) is a bactericidal serine protease stored in the neutrophil azurophilic granules. CTSG regulates inflammation, activating matrix metalloproteinases (MMPs...

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Detalles Bibliográficos
Autores principales: Pérez-Is, Laura, Ocaña, Marcos G., Montes, A. Hugo, Carton, José A., Álvarez, Victoria, Meana, Álvaro, Fierer, Joshua, Valle-Garay, Eulalia, Asensi, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812796/
https://www.ncbi.nlm.nih.gov/pubmed/31647805
http://dx.doi.org/10.1371/journal.pone.0220022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812796/
https://www.ncbi.nlm.nih.gov/pubmed/31647805
http://dx.doi.org/10.1371/journal.pone.0220022

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