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Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

Colorectal cancer (CRC) is the second leading cause of cancer deaths in the US with the majority of deaths due to metastatic disease. Current chemotherapeutic regimens involve highly toxic agents, which limits their utility; therefore, more effective and less toxic agents are required to see a reduc...

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Detalles Bibliográficos
Autores principales: Sinner, Heather F., Johnson, Jeremy, Rychahou, Piotr G., Watt, David S., Zaytseva, Yekaterina Y., Liu, Chunming, Evers, B. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812860/
https://www.ncbi.nlm.nih.gov/pubmed/31648230
http://dx.doi.org/10.1371/journal.pone.0224253