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Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation
Colorectal cancer (CRC) is the second leading cause of cancer deaths in the US with the majority of deaths due to metastatic disease. Current chemotherapeutic regimens involve highly toxic agents, which limits their utility; therefore, more effective and less toxic agents are required to see a reduc...
Autores principales: | Sinner, Heather F., Johnson, Jeremy, Rychahou, Piotr G., Watt, David S., Zaytseva, Yekaterina Y., Liu, Chunming, Evers, B. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812860/ https://www.ncbi.nlm.nih.gov/pubmed/31648230 http://dx.doi.org/10.1371/journal.pone.0224253 |
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