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How Well Do Routine Molecular Diagnostics Detect Rifampin Heteroresistance in Mycobacterium tuberculosis?

Rifampin heteroresistance—where rifampin-resistant and -susceptible tuberculosis (TB) bacilli coexist—may result in failed standard TB treatment and potential spread of rifampin-resistant strains. The detection of rifampin heteroresistance in routine rapid diagnostic tests (RDTs) allows for patients...

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Detalles Bibliográficos
Autores principales: Ng, Kamela C. S., Supply, Philip, Cobelens, Frank G. J., Gaudin, Cyril, Gonzalez-Martin, Julian, de Jong, Bouke C., Rigouts, Leen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812990/
https://www.ncbi.nlm.nih.gov/pubmed/31413081
http://dx.doi.org/10.1128/JCM.00717-19