The role of exosomal PD-L1 in tumor progression and immunotherapy

Programmed death ligand 1 (PD-L1), a type I transmembrane protein, binds to its receptor PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis. In contrast, tumor cells highly express PD-L1, which binds to receptor PD-1 expressed on activated T cells, leading to i...

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Detalles Bibliográficos
Autores principales: Xie, Feiting, Xu, Mengxue, Lu, Jian, Mao, Lingxiang, Wang, Shengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813045/
https://www.ncbi.nlm.nih.gov/pubmed/31647023
http://dx.doi.org/10.1186/s12943-019-1074-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813045/
https://www.ncbi.nlm.nih.gov/pubmed/31647023
http://dx.doi.org/10.1186/s12943-019-1074-3

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