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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor

BACKGROUND: The goal of this study is to use comprehensive molecular profiling to characterize clinical response to anti-TNF therapy in a real-world setting and identify reproducible markers differentiating good responders and non-responders in rheumatoid arthritis (RA). METHODS: Whole-blood mRNA, p...

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Detalles Bibliográficos
Autores principales: Farutin, Victor, Prod’homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J., Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A., Gunay, Nur Sibel, Hillson, Jan L., DeLuca, David S., Saunders, Katherine C., Pappas, Dimitrios A., Greenberg, Jeffrey D., Kremer, Joel M., Manning, Anthony M., Ling, Leona E., Capila, Ishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813112/
https://www.ncbi.nlm.nih.gov/pubmed/31647025
http://dx.doi.org/10.1186/s13075-019-1999-3