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Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor
BACKGROUND: The goal of this study is to use comprehensive molecular profiling to characterize clinical response to anti-TNF therapy in a real-world setting and identify reproducible markers differentiating good responders and non-responders in rheumatoid arthritis (RA). METHODS: Whole-blood mRNA, p...
Autores principales: | Farutin, Victor, Prod’homme, Thomas, McConnell, Kevin, Washburn, Nathaniel, Halvey, Patrick, Etzel, Carol J., Guess, Jamey, Duffner, Jay, Getchell, Kristen, Meccariello, Robin, Gutierrez, Bryan, Honan, Christopher, Zhao, Ganlin, Cilfone, Nicholas A., Gunay, Nur Sibel, Hillson, Jan L., DeLuca, David S., Saunders, Katherine C., Pappas, Dimitrios A., Greenberg, Jeffrey D., Kremer, Joel M., Manning, Anthony M., Ling, Leona E., Capila, Ishan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813112/ https://www.ncbi.nlm.nih.gov/pubmed/31647025 http://dx.doi.org/10.1186/s13075-019-1999-3 |
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