IMAGE: high-powered detection of genetic effects on DNA methylation using integrated methylation QTL mapping and allele-specific analysis

Identifying genetic variants that are associated with methylation variation—an analysis commonly referred to as methylation quantitative trait locus (mQTL) mapping—is important for understanding the epigenetic mechanisms underlying genotype-trait associations. Here, we develop a statistical method,...

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Detalles Bibliográficos
Autores principales: Fan, Yue, Vilgalys, Tauras P., Sun, Shiquan, Peng, Qinke, Tung, Jenny, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813132/
https://www.ncbi.nlm.nih.gov/pubmed/31651351
http://dx.doi.org/10.1186/s13059-019-1813-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813132/
https://www.ncbi.nlm.nih.gov/pubmed/31651351
http://dx.doi.org/10.1186/s13059-019-1813-1

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