TNFα Induces Multidrug Resistance-Associated Protein 4 Expression through p38-E2F1-Nrf2 Signaling in Obstructive Cholestasis

PURPOSE: To explore the molecular mechanism of the upregulation of multidrug resistance-associated protein 4 (MRP4) in cholestasis. MATERIALS AND METHODS: The mRNA and protein levels of MRP4 in liver samples from cholestatic patients were determined by quantitative real-time PCR and Western blot. In...

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Detalles Bibliográficos
Autores principales: Lian, Wei, Liu, Xiaocong, Chen, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813138/
https://www.ncbi.nlm.nih.gov/pubmed/31637886
http://dx.doi.org/10.3349/ymj.2019.60.11.1045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813138/
https://www.ncbi.nlm.nih.gov/pubmed/31637886
http://dx.doi.org/10.3349/ymj.2019.60.11.1045

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