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Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling

Defective interfering particles (DIPs) are a natural byproduct of influenza A virus (IAV) replication. DIPs interfere with the propagation and spread of infectious standard virus (STV), reduce virus yields by competing for viral and cellular resources, and induce antiviral responses. These propertie...

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Detalles Bibliográficos
Autores principales: Tapia, Felipe, Laske, Tanja, Wasik, Milena A., Rammhold, Markus, Genzel, Yvonne, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813217/
https://www.ncbi.nlm.nih.gov/pubmed/31681751
http://dx.doi.org/10.3389/fbioe.2019.00275