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Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling
Defective interfering particles (DIPs) are a natural byproduct of influenza A virus (IAV) replication. DIPs interfere with the propagation and spread of infectious standard virus (STV), reduce virus yields by competing for viral and cellular resources, and induce antiviral responses. These propertie...
Autores principales: | Tapia, Felipe, Laske, Tanja, Wasik, Milena A., Rammhold, Markus, Genzel, Yvonne, Reichl, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813217/ https://www.ncbi.nlm.nih.gov/pubmed/31681751 http://dx.doi.org/10.3389/fbioe.2019.00275 |
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