Methylprednisolone Decreases Mitochondria-Mediated Apoptosis and Autophagy Dysfunction in Hepatocytes of Experimental Autoimmune Hepatitis Model via the Akt/mTOR Signaling

Autoimmune hepatitis (AIH) is characterized by massive immune cell-mediated hepatocyte destruction. Glucocorticoids, particularly methylprednisolone (MP), are the most effective treatment for AIH; however, the mechanism underlying the effects of glucocorticoid treatment has not been fully elucidated...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoli, Men, Ruoting, Wang, Haoran, Shen, Mengyi, Wang, Tingting, Ye, Tinghong, Luo, Xuefeng, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813226/
https://www.ncbi.nlm.nih.gov/pubmed/31680966
http://dx.doi.org/10.3389/fphar.2019.01189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813226/
https://www.ncbi.nlm.nih.gov/pubmed/31680966
http://dx.doi.org/10.3389/fphar.2019.01189

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