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Albumin Exchange in Alzheimer's Disease: Might CSF Be an Alternative Route to Plasma?
Amyloid β (Aβ) in brain parenchyma is thought to play a central role in the pathogenesis of Alzheimer's disease (AD). Aβ is transported from the brain to the plasma via complex transport mechanisms at the blood-brain barrier (BBB). About 90–95% of plasma Aβ may be bound to albumin. Replacement...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813234/ https://www.ncbi.nlm.nih.gov/pubmed/31681137 http://dx.doi.org/10.3389/fneur.2019.01036 |