High-performance chemical- and light-inducible recombinases in mammalian cells and mice

Site-specific DNA recombinases are important genome engineering tools. Chemical- and light-inducible recombinases, in particular, enable spatiotemporal control of gene expression. However, inducible recombinases are scarce due to the challenge of engineering high performance systems, thus constraini...

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Detalles Bibliográficos
Autores principales: Weinberg, Benjamin H., Cho, Jang Hwan, Agarwal, Yash, Pham, N. T. Hang, Caraballo, Leidy D., Walkosz, Maciej, Ortega, Charina, Trexler, Micaela, Tague, Nathan, Law, Billy, Benman, William K. J., Letendre, Justin, Beal, Jacob, Wong, Wilson W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813296/
https://www.ncbi.nlm.nih.gov/pubmed/31649244
http://dx.doi.org/10.1038/s41467-019-12800-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813296/
https://www.ncbi.nlm.nih.gov/pubmed/31649244
http://dx.doi.org/10.1038/s41467-019-12800-7

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