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Lysosome restoration to activate podocyte autophagy: a new therapeutic strategy for diabetic kidney disease

Autophagy, the intracellular lysosomal degradation process plays a pivotal role in podocyte homeostasis in diabetic kidney disease (DKD). Lysosomal function, autophagic activity, and their actions were investigated in vitro and in vivo. We found that LC3-II- and p62-positive vacuoles accumulated in...

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Detalles Bibliográficos
Autores principales:	Liu, Wei Jing, Gan, Yu, Huang, Wei Fang, Wu, Hong-luan, Zhang, Xue-qin, Zheng, Hui Juan, Liu, Hua-feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813305/ https://www.ncbi.nlm.nih.gov/pubmed/31649253 http://dx.doi.org/10.1038/s41419-019-2002-6

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