The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II

Mitochondria play a pivotal role in cancer bioenergetics and are considered a potential target for anticancer therapy. Considering the limited efficacy and toxicity of currently available mitochondria-targeting agents, it is necessary to develop effective mitochondria-targeting anticancer drugs. By...

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Detalles Bibliográficos
Autores principales: Min, Hye-Young, Jang, Hyun-Ji, Park, Kwan Hee, Hyun, Seung Yeob, Park, So Jung, Kim, Ji Hye, Son, Jaekyoung, Kang, Sam Sik, Lee, Ho-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813327/
https://www.ncbi.nlm.nih.gov/pubmed/31649278
http://dx.doi.org/10.1038/s41419-019-2041-z