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The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II
Mitochondria play a pivotal role in cancer bioenergetics and are considered a potential target for anticancer therapy. Considering the limited efficacy and toxicity of currently available mitochondria-targeting agents, it is necessary to develop effective mitochondria-targeting anticancer drugs. By...
Autores principales: | Min, Hye-Young, Jang, Hyun-Ji, Park, Kwan Hee, Hyun, Seung Yeob, Park, So Jung, Kim, Ji Hye, Son, Jaekyoung, Kang, Sam Sik, Lee, Ho-Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813327/ https://www.ncbi.nlm.nih.gov/pubmed/31649278 http://dx.doi.org/10.1038/s41419-019-2041-z |
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