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Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus

It is assumed that intracellular pathogenic bacteria have to cope with DNA alkylating stress within host cells. Here we use single-cell reporter systems to show that the pathogen Brucella abortus does encounter alkylating stress during the first hours of macrophage infection. Genes encoding direct r...

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Detalles Bibliográficos
Autores principales: Poncin, Katy, Roba, Agnès, Jimmidi, Ravikumar, Potemberg, Georges, Fioravanti, Antonella, Francis, Nayla, Willemart, Kévin, Zeippen, Nicolas, Machelart, Arnaud, Biondi, Emanuele G., Muraille, Eric, Vincent, Stéphane P., De Bolle, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813329/
https://www.ncbi.nlm.nih.gov/pubmed/31649248
http://dx.doi.org/10.1038/s41467-019-12516-8