Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis

Maintenance of cellular proteostasis is achieved by a multi-layered quality control network, which counteracts the accumulation of misfolded proteins by refolding and degradation pathways. The organized sequestration of misfolded proteins, actively promoted by cellular sequestrases, represents a thi...

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Detalles Bibliográficos
Autores principales: Ho, Chi-ting, Grousl, Tomas, Shatz, Oren, Jawed, Areeb, Ruger-Herreros, Carmen, Semmelink, Marije, Zahn, Regina, Richter, Karsten, Bukau, Bernd, Mogk, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813348/
https://www.ncbi.nlm.nih.gov/pubmed/31649258
http://dx.doi.org/10.1038/s41467-019-12868-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813348/
https://www.ncbi.nlm.nih.gov/pubmed/31649258
http://dx.doi.org/10.1038/s41467-019-12868-1

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