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Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis
Maintenance of cellular proteostasis is achieved by a multi-layered quality control network, which counteracts the accumulation of misfolded proteins by refolding and degradation pathways. The organized sequestration of misfolded proteins, actively promoted by cellular sequestrases, represents a thi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813348/ https://www.ncbi.nlm.nih.gov/pubmed/31649258 http://dx.doi.org/10.1038/s41467-019-12868-1 |