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Structural Dynamics of the N-Extension of Cardiac Troponin I Complexed with Troponin C by Site-Directed Spin Labeling Electron Paramagnetic Resonance

The secondary structure of the N-extension of cardiac troponin I (cTnI) was determined by measuring the distance distribution between spin labels attached to the i and i + 4 residues: 15/19, 23/27, 27/31, 35/39, and 43/47. All of the EPR spectra of these regions in the monomeric state were broadened...

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Detalles Bibliográficos
Autores principales: Zhao, Chenchao, Somiya, Takayasu, Takai, Shinji, Ueki, Shoji, Arata, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813352/
https://www.ncbi.nlm.nih.gov/pubmed/31649274
http://dx.doi.org/10.1038/s41598-019-51740-6