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Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function

Fracture repair is initiated by a multitude of immune cells and induction of an inflammatory cascade. Alterations in the early healing response due to an aged adaptive immune system leads to impaired bone repair, delayed healing or even formation of non-union. However, immuno-senescence is not limit...

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Detalles Bibliográficos
Autores principales: Löffler, Julia, Sass, F. Andrea, Filter, Sebastian, Rose, Alexander, Ellinghaus, Agnes, Duda, Georg N., Dienelt, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813416/
https://www.ncbi.nlm.nih.gov/pubmed/31681320
http://dx.doi.org/10.3389/fimmu.2019.02443