The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling

B-cell receptor (BCR)-dependent signaling is central for leukemia B-cell homeostasis, as underscored by the promising clinical results obtained in patients with chronic lymphocytic leukemia (CLL) treated with novel agents targeting components of this pathway. Herein, we demonstrate that the mithralo...

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Detalles Bibliográficos
Autores principales: Lorenzo-Herrero, Seila, Sordo-Bahamonde, Christian, Bretones, Gabriel, Payer, Ángel R., González-Rodríguez, Ana P., González-García, Esther, Pérez-Escuredo, Jhudit, Villa-Álvarez, Mónica, Núñez, Luz-Elena, Morís, Francisco, Gonzalez, Segundo, López-Soto, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813538/
https://www.ncbi.nlm.nih.gov/pubmed/31681329
http://dx.doi.org/10.3389/fimmu.2019.02455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813538/
https://www.ncbi.nlm.nih.gov/pubmed/31681329
http://dx.doi.org/10.3389/fimmu.2019.02455

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