Activatable Photosensitizer for Targeted Ablation of lacZ-Positive Cells with Single-Cell Resolution

[Image: see text] To achieve highly selective ablation of lacZ-positive cells in a biological milieu in vivo, we developed an activatable photosensitizer, SPiDER-killer-βGal, targeted to β-galactosidase encoded by the lacZ reporter gene. Hydrolysis of SPiDER-killer-βGal by β-galactosidase simultaneo...

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Detalles Bibliográficos
Autores principales: Chiba, Mayumi, Kamiya, Mako, Tsuda-Sakurai, Kayoko, Fujisawa, Yuya, Kosakamoto, Hina, Kojima, Ryosuke, Miura, Masayuki, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813548/
https://www.ncbi.nlm.nih.gov/pubmed/31660435
http://dx.doi.org/10.1021/acscentsci.9b00678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813548/
https://www.ncbi.nlm.nih.gov/pubmed/31660435
http://dx.doi.org/10.1021/acscentsci.9b00678

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