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An osteogenic helioxanthin derivative suppresses the formation of bone-resorbing osteoclasts

OBJECTIVE: The helioxanthin derivative 4-(4-methoxyphenyl)thieno[2,3-b:5,4-c′]dipyridine-2-carboxamide (TH) is a low-molecular-weight compound that was identified through screening for osteogenic compounds that enhance the activity of mouse preosteoblastic MC3T3-E1 cells. In the present study, we fo...

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Detalles Bibliográficos
Autores principales: Amano, Hitoshi, Iwaki, Futoshi, Oki, Meiko, Aoki, Kazuhiro, Ohba, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813560/
https://www.ncbi.nlm.nih.gov/pubmed/31667208
http://dx.doi.org/10.1016/j.reth.2019.08.007