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Continuous‐Flow Pd‐Catalyzed Carbonylation of Aryl Chlorides with Carbon Monoxide at Elevated Temperature and Pressure

The development of a continuous‐flow protocol for a palladium‐catalyzed methoxycarbonylation of (hetero)aryl chlorides using carbon monoxide gas and methanol is described. (Hetero)aryl chlorides are the least expensive of the aryl halides, but are underutilized in carbonylation reactions due to thei...

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Detalles Bibliográficos
Autores principales: Mata, Alejandro, Hone, Christopher A., Gutmann, Bernhard, Moens, Luc, Kappe, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813631/
https://www.ncbi.nlm.nih.gov/pubmed/31681449
http://dx.doi.org/10.1002/cctc.201801974