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Mining Public Toxicogenomic Data Reveals Insights and Challenges in Delineating Liver Steatosis Adverse Outcome Pathways

Exposure to chemicals contributes to the development and progression of fatty liver, or steatosis, a process characterized by abnormal accumulation of lipids within liver cells. However, lack of knowledge on how chemicals cause steatosis has prevented any large-scale assessment of the 80,000+ chemic...

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Detalles Bibliográficos
Autores principales: AbdulHameed, Mohamed Diwan M., Pannala, Venkat R., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813744/
https://www.ncbi.nlm.nih.gov/pubmed/31681434
http://dx.doi.org/10.3389/fgene.2019.01007